BOOKS & ELECTRONIC MEDIA

The collectors of lost souls: turning kuru scientists into whitemen

Thomas P Weber^*

Joint Research Centre, European Commission, Ispra, Italy

Author: Warwick Anderson
Publisher: The Johns Hopkins University Press, Baltimore, MD, 2008
ISBN: 978-0801890406; hardback; 328 pages; US$ 24.95

Kuru, later known to be an incurable degenerative neurological disorder transmitted by prions, was first noted in the Fore people of Papua New Guinea by Australian administrators and a few anthropologists exploring the area in the 1950s. The young, adventurous American doctor, Daniel Carleton Gajdusek (1923-2008), first came to Papua New Guinea in 1957, planning to make only a short stop there on his way from Australia to the United States of America (USA). Gajdusek had learned to love the excitement offered by epidemiological investigations in challenging circumstances in Afghanistan, the Islamic Republic of Iran and Turkey. Rapidly enchanted by the Fore and the tropical environment, Gajdusek became fascinated by the bizarre epidemic, which particularly afflicted women and children. The study of kuru became a life-long passion of the brilliant, flamboyant and troubled doctor. His scientific passion culminated in the award of the Nobel Prize in 1976, although his deep entanglement with the Fore people led to accusations and a subsequent conviction of child molestation in 1996.

The story of kuru and of prions has been told many times from the scientific perspective. The human side of the story, encompassing a remarkable cast of Fore people, colonial officials and researchers, is equally intriguing. Gajdusek, and later Stanley Prusiner, attracted most of the attention while the Fore people provided the exotic background. Especially after the bovine spongiform encephalopathy (known as mad-cow disease) crisis, the Fore people became increasingly sidelined and their story was all too often reduced to the phenomenon of ritual cannibalism.

In his book, Warwick Anderson, a medical doctor and science historian, recounts the complexity of the story by portraying how scientists learned about kuru, not what they found out or who got it right. Anderson offers an absorbing account of kuru that is partly a biography of Gajdusek, and partly a historical and anthropological story of an encounter between the two worlds of modern biomedicine and a Melanesian culture.

Gajdusek was enmeshed in two fragile and complex systems of gift exchange. The concept of "the gift" has long been an entry point into the anthropological study of Melanesian cultures. Unlike commodities, gifts establish a relationship between the exchanging subjects and do not primarily satisfy desires. But gift economies are not restricted to pre-modern societies. Anderson thus draws parallels between the gift economy of the Fore and the practices of biomedicine in the 1950s and 1960s. To build his scientific reputation, Gajdusek had to enter into exchange relationships with his colleagues in Australia and the USA. To achieve this aim, he also had to participate in the gift economy of the Fore. For the Fore, each person is a microcosm of relations that have been activated through individual agents. Gifts produce such relations and as a result "make" persons. Gajdusek was allowed to receive the brains that made his research possible (and also increased his repudiation) because he gained the trust of many Fore people through gift exchange and, as a consequence, became a true person in their view. However, as soon as the Fore body parts passed from one exchange regime to the other (the modern scientific community), they became alienated and were no longer considered parts of persons. Gajdusek could never disentangle himself from the reciprocal relationship with the Fore and for him the specimen always reminded him of the person from whom they came - people for whom he often cared in the last agonizing days of their lives.

This emphasis on the gift economy may seem arcane but it has wide-ranging consequences. First, it demonstrates how the commodification of biological items - genes, cells or tissues - has altered the way science is done since the 1960s. The relationship between scientists is no longer exclusively based on reciprocal trust. The biological materials that earlier were exchanged to form and foster relationships have now become commodities. Second, the gift economy of the Fore challenges fundamental assumptions of bioethics. Unlike in classic Eurocentric social theory, there are no stable, autonomous individuals in Melanesian social practice. In this context, "informed consent" becomes a somewhat unsuitable principle for the framing and resolution of bioethical questions. People build trust through gift exchange. In Gajdusek's case, this trust then served as the basis for the passage of body parts to him and the global scientific enterprise.

Anderson's book is a valuable and sometimes provocative contribution to the study of science and medicine in colonial and post-colonial contexts. He shows how the relationships between scientific researchers and their "tribal" research subjects have changed in the past 50 years. Modern bioethics has constructed welcome limits to research activities in this regard, but these limits are often defined purely from the perspective of the western world. Anderson gives an eloquent voice to other concepts and shows that truly global bioethics still face many challenges.

* Correspondence to Thomas Weber (e-mail: Thomas.Weber@jrc.ec.europa.eu).