Progress in knowledge on the relationship between Zika virus infection during pregnancy and severe congenital neurological disorder (thus far referred to by its principal sign, microcephaly) has been so rapid, serious, and consistent that it is sure to make health history. The story began in August-September 2015, when obstetricians and neonatologists in Pernambuco State, Brazil, observed an increase in the number of congenital malformations, followed by an alert issued by the Pernambuco State Health Department and the Ministry of Health in October, launching an investigation into the problem. By November 11 there was already sufficient evidence for Brazil to declare a Public Health Emergency of National Concern. On February 1st, 2016, the World Health Organization declared a Public Health Emergency of International Concern (PHEIC), basing its decision on the same criteria as the Brazilian declaration ¹1 World Health Organzation. WHO Director-General summarizes the outcome of the Emergency Committee regarding clusters of microcephaly and Guillain-Barré syndrome. http://www.who.int/mediacentre/news/statements/2016/emergency-committee-zika-microcephaly/en/ (acessado em 04/Mar/2016).
http://www.who.int/mediacentre/news/stat... .

The virus already existed and circulated in various countries of Africa and Asia, so why was this excessive number of microcephaly cases only reported in Brazil? First, although the frequency of fetal malformations is high among women with a history of Zika virus infection early in pregnancy, the hardest-hit countries at the onset of the epidemic, especially the island nations of Micronesia and Polynesia, have small populations, and malformations there are rare. Retrospectively, however, the virus was detected in some cases of fetal malformations that occurred in those countries during the 2013 outbreak ²2 Jouannic J-M, Friszer S, Leparc-Goffart I, Garel C, Eyrolle-Guignot D. Zika virus infection in French Polynesia. Lancet 2016; 387:1051-2.. But Brazilian Unified National Health System (SUS) has also played an essential role, since it provides most of the childbirth care in the country, especially among the poorest population. This broad-reaching health system revealed the bigger picture and raised epidemiological suspicion. Brazil also has serious and high-quality research, capable of combining epidemiological investigation and health care, without losing sight of the patient's central importance. A recent event organized by the team at the epicenter of this "earthquake" in Recife (Pernambuco), called the Workshop on the A, B, C, D, and E of the Zika Virus (http://scf.cpqam.fiocruz.br/eventozika/), discussed what is being done in research, from virology to serology, from clinical practice to epidemiology. And much is being done.

From the onset of the outbreak, the Editorial Board of CSP decided that articles dealing with any aspect of Zika would follow a "fast track" review. This edition of our journal features three articles addressing different questions. The paper Microcephaly in Pernambuco State, Brazil: Epidemiological Characteristics and Evaluation of the Diagnostic Accuracy of Cutoff Points for Reporting Suspected Cases discusses the technical grounds for redefining the cutoff point for suspected cases of microcephaly. In the midst of accusations in the gutter press and internet that data were being manipulated to hide the epidemic, the authors present the scientific basis for the protocol adopted by the Brazilian Ministry of Health to define suspected cases. Starting with the submission through the peer review and reformulation, the article was approved in just 28 days.

The other two papers, published in the Perspectives section, address policy issues that touch the Zika epidemic tangentially. The response to international health emergencies involves the securitization of health. The Ebola epidemic was classified as a threat to world peace and security, and the consequences are analyzed very clearly in the paper From Ebola to Zika: International Emergencies and the Securitization of Global Health. The other paper discusses the Threats of Retrocession in Sexual and Reproductive Health Policies in Brazil During the Zika Epidemic. Such threats are embodied in Bill of Law n. 5,069/2013, which increases the barriers for accessing health services and the exercise of sexual and reproductive rights by victims of sexual assault. The bill goes so far as to encourage conscientious objection by professionals in public health care services, thereby denying Brazil's secularity ³3 Diniz D. Estado laico, objeção de consciência e políticas de saúde. Cad Saúde Pública 2013; 29:1704-6..

In short, the doors are open to fast track processing of articles on Zika. We hope to contribute to the scientific debate, with the unswerving goals of scientific progress and the population's health

Marilia Sá Carvalho
Editora

Publication Dates