Salud Pública de Méxicohttps://scielosp.org/feed/spm/2018.v60n1/2021-01-13T00:10:00ZVol. 60 No. 1 - 2018WerkzeugEl CISEI: referente en investigación sobre enfermedades infecciosas en el siglo XXI10.21149/92342021-01-13T00:10:00Z2017-01-20T00:02:00ZSantos Preciado, José Ignacio
<em>Santos Preciado, José Ignacio</em>;
<br/><br/>
Centro de Investigación sobre Enfermedades Infecciosas: 33 años formando recursos humanos y generando conocimiento científico10.21149/93422021-01-13T00:10:00Z2017-01-20T00:02:00ZAlpuche Aranda, Celia M.
<em>Alpuche Aranda, Celia M.</em>;
<br/><br/>
High relative abundance of firmicutes and increased TNF-α levels correlate with obesity in children10.21149/81332021-01-13T00:10:00Z2017-01-20T00:02:00ZOrbe-Orihuela, Yaneth CLagunas-Martínez, AlfredoBahena-Román, MargaritaMadrid-Marina, VicenteTorres-Poveda, KirvisFlores-Alfaro, EugeniaMéndez-Padrón, AraceliDíaz-Benítez, Cinthya EPeralta-Zaragoza, OscarAntúnez-Ortiz, DianaCruz, MiguelBurguete-García, Ana I
<em>Orbe-Orihuela, Yaneth C</em>;
<em>Lagunas-Martínez, Alfredo</em>;
<em>Bahena-Román, Margarita</em>;
<em>Madrid-Marina, Vicente</em>;
<em>Torres-Poveda, Kirvis</em>;
<em>Flores-Alfaro, Eugenia</em>;
<em>Méndez-Padrón, Araceli</em>;
<em>Díaz-Benítez, Cinthya E</em>;
<em>Peralta-Zaragoza, Oscar</em>;
<em>Antúnez-Ortiz, Diana</em>;
<em>Cruz, Miguel</em>;
<em>Burguete-García, Ana I</em>;
<br/><br/>
Abstract: Objective: To investigate the correlation among pro- or anti-inflammatory cytokines and the two main gut microbiota phyla in obese children. Materials and methods: Anthropometric data were obtained from 890 children under 14 years old to determine the degree of obesity. Serum cytokine concentration was measured by ELISA. Relative abundance of gut microbiota in feces was evaluated by quantitative Real-Time PCR assays. Results: Anthropometric and biochemical parameters were statistically higher in overweight /obese children than in lean ones. Increased TNF-α levels were found in obese children that also have a high relative abundance of Firmicutes. Conclusions: Obese children have a high relative abundance of Firmicutes that correlates with increased levels of TNF-α. This is the first study that shows a relation between Firmicute abundance and TNF-α serum concentration in obese children.Association of dengue fever with Aedes spp. abundance and climatological effects10.21149/81412021-01-13T00:10:00Z2017-01-20T00:02:00ZBetanzos-Reyes, Ángel FranciscoRodríguez, Mario HenryRomero-Martínez, MartínSesma-Medrano, EduardoRangel-Flores, HildaSantos-Luna, René
<em>Betanzos-Reyes, Ángel Francisco</em>;
<em>Rodríguez, Mario Henry</em>;
<em>Romero-Martínez, Martín</em>;
<em>Sesma-Medrano, Eduardo</em>;
<em>Rangel-Flores, Hilda</em>;
<em>Santos-Luna, René</em>;
<br/><br/>
Abstract: Objective: To analyze the association of dengue fever incidence with Aedes mosquito’s abundance, and the effect of climatological and geographical variables, in a region in Morelos State, Mexico. Materials and methods: Weekly data during the period 2010 to 2014 was used. Mosquito abundance was determined using ovitraps. Confirmed dengue cases were obtained from the Epidemiological Surveillance System. Climatic variables were obtained from weather monitoring stations. The correlation between climate variables and ovitraps data was estimated using a multivariate regression model. Results: A correlation of mosquito abundance with dengue fever incidence, and a yearly pattern with seasonal variations were observed. The daily mean temperature, relative humidity and rainfall parameters were associated with mosquito egg abundance. Time lags of three and four weeks between egg counts and dengue fever incidence were observed. Conclusion: Time lags between egg counts and dengue incidence could be useful for prevention and control interventions.Streptococcus pneumoniae: distribution of serotypes and antimicrobial susceptibility in patients with cáncer10.21149/81592021-01-13T00:10:00Z2017-01-20T00:02:00ZSoto-Noguerón, AraceliCarnalla-Barajas, María NoemíCornejo-Juárez, PatriciaVolkow-Fernández, PatriciaVelázquez-Meza, María ElenaEchániz-Aviles, Gabriela
<em>Soto-Noguerón, Araceli</em>;
<em>Carnalla-Barajas, María Noemí</em>;
<em>Cornejo-Juárez, Patricia</em>;
<em>Volkow-Fernández, Patricia</em>;
<em>Velázquez-Meza, María Elena</em>;
<em>Echániz-Aviles, Gabriela</em>;
<br/><br/>
Abstract: Objective: To describe the distribution of pneumococcal serotypes causing infectious diseases in patients with hematological malignancies and solid tumors and their antimicrobial susceptibility before and after introduction of pneumococcal conjugate vaccine (PCV7) in Mexico. Materials and methods: Consecutive pneumococcal isolates from hospitalized patients from the SIREVA-network were serotyped using the Quellung reaction and antimicrobial susceptibility was performed using the broth microdilution method. Results: A total of 175 pneumococcal isolates were recovered, 105 from patients with hematological malignancies and 70 with solid tumors. Serotypes 19A (22.7%), 19F (20.4%), and 35B (17.7%) were the most frequent isolates in the first group and serotypes 3 (27.2%) and 19A (28.6%) in the second group. No decreased susceptibility to beta-lactams or TMP/SMX was observed after introduction of PCV7. Conclusions: An increase in non-vaccine types is observed without significate changes in antimicrobial susceptibility after introduction of PCV7.Klebsiella variicola and Klebsiella quasipneumoniae with capacity to adapt to clinical and plant settings10.21149/81562021-01-13T00:10:00Z2017-01-20T00:02:00ZMartínez-Romero, EsperanzaRodríguez-Medina, NadiaBeltrán-Rojel, MarilúToribio-Jiménez, JeiryGarza-Ramos, Ulises
<em>Martínez-Romero, Esperanza</em>;
<em>Rodríguez-Medina, Nadia</em>;
<em>Beltrán-Rojel, Marilú</em>;
<em>Toribio-Jiménez, Jeiry</em>;
<em>Garza-Ramos, Ulises</em>;
<br/><br/>
Abstract: Objective: To compare the genetic determinants involved in plant colonization or virulence in the reported genomes of K. variicola, K. quasipneumoniae and K. pneumoniae. Materials and methods: In silico comparisons and Jaccard analysis of genomic data were used. Fimbrial genes were detected by PCR. Biological assays were performed with plant and clinical isolates. Results: Plant colonization genes such as cellulases, catalases and hemagglutinins were mainly present in K. variicola genomes. Chromosomal β-lactamases were characteristic of this species and had been previously misclassified. K. variicola and K. pneumoniae isolates produced plant hormones. Conclusions: A mosaic distribution of different virulence- and plant-associated genes was found in K. variicola and in K. quasipneumoniae genomes. Some plant colonizing genes were found mainly in K. variicola genomes. The term plantanosis is proposed for plant-borne human infections.Dengue virus infection induces chromatin remodeling at locus AAEL006536 in the midgut of Aedes aegypti10.21149/84712021-01-13T00:10:00Z2017-01-20T00:02:00ZGleason-Rodríguez, GracielaCastillo-Méndez, ManuelMaya, KrystalRamos-Castañeda, JoséValverde-Garduño, Verónica
<em>Gleason-Rodríguez, Graciela</em>;
<em>Castillo-Méndez, Manuel</em>;
<em>Maya, Krystal</em>;
<em>Ramos-Castañeda, José</em>;
<em>Valverde-Garduño, Verónica</em>;
<br/><br/>
Abstract: Objective: To identify and characterize Aedes aegypti’s AAEL006536 gene proximal upstream cis-regulatory sequences activated by dengue virus infection. Materials and methods: A. aegypti Rockefeller strain mosquitoes were blood fed or infected with dengue virus 2. Open chromatin profiling was then carried out in pools of midguts from each group of mosquitoes. Results: The proximal upstream region does not contain open chromatin sites in the midguts of blood-fed mosquitoes as detected by FAIRE-qPCR. In contrast, two cis-regulatory sites were identified in the same upstream region of dengue virus-infected mosquito midguts. The distal sequence contains STAT-, REL- and C/EBP-type transcription factor binding sites. Conclusion: The activation of two proximal cis-regulatory sequences, induced by dengue virus infection, is mediated by chromatin remodeling mechanisms. Binding sites suggest a dengue virus infection-induced participation of immunity transcription factors in the up-regulation of this gene. This suggests the participation of the AAEL006536 gene in the mosquito’s antiviral innate immune response.Ecdysis-related pleiotropic neuropeptides expression during Anopheles albimanus development10.21149/81342021-01-13T00:10:00Z2017-01-20T00:02:00ZAlvarado-Delgado, AlejandroMoran-Francia, KenPerales-Ortiz, GuillermoRodríguez, Mario HenryLanz-Mendoza, Humberto
<em>Alvarado-Delgado, Alejandro</em>;
<em>Moran-Francia, Ken</em>;
<em>Perales-Ortiz, Guillermo</em>;
<em>Rodríguez, Mario Henry</em>;
<em>Lanz-Mendoza, Humberto</em>;
<br/><br/>
Abstract: Objective: To analyze the transcription pattern of neuropeptides in the ontogeny of a malaria vector, the mosquito Anopheles albimanus. Materials and methods: The transcription pattern of Crustacean CardioActive peptide (CCAP), corazonin, Ecdysis Triggering Hormone (ETH), allatostatin-A, orcokinin, Insulin Like Peptide 2 (ILP2), Insulin Like Peptide 5 (ILP5) and bursicon was evaluated using qPCR on larvae (1st - 4th instar), pupae and adult mosquitoes. Results: Unlike in other insects, transcripts of CCAP (70.8%), ETH (60.2%) and corazonin (76.5%) were expressed in 4th instar larvae, probably because these three neuropeptides are associated with the beginning of ecdysis. The neuropeptide ILP2 showed higher transcription levels in other stages and orcokinin decreased during the development of the mosquito. Conclusion: The CCAP, corazonin and ETH neuropeptides are potential targets for the design of control strategies aimed at disrupting An. albiamnus larval development.Genome misclassification of Klebsiella variicola and Klebsiella quasipneumoniae isolated from plants, animals and humans10.21149/81492021-01-13T00:10:00Z2017-01-20T00:02:00ZMartínez-Romero, EsperanzaRodríguez-Medina, NadiaBeltrán-Rojel, MariluSilva-Sánchez, JesúsBarrios-Camacho, HumbertoPérez-Rueda, ErnestoGarza-Ramos, Ulises
<em>Martínez-Romero, Esperanza</em>;
<em>Rodríguez-Medina, Nadia</em>;
<em>Beltrán-Rojel, Marilu</em>;
<em>Silva-Sánchez, Jesús</em>;
<em>Barrios-Camacho, Humberto</em>;
<em>Pérez-Rueda, Ernesto</em>;
<em>Garza-Ramos, Ulises</em>;
<br/><br/>
Abstract: Objective: Due to the fact that K. variicola, K. quasipneumoniae and K. pneumoniae are closely related bacterial species, misclassification can occur due to mistakes either in normal biochemical tests or during submission to public databases. The objective of this work was to identify K. variicola and K. quasipneumoniae genomes misclassified in GenBank database. Materials and methods: Both rpoB phylogenies and average nucleotide identity (ANI) were used to identify a significant number of misclassified Klebsiella spp. genomes. Results: Here we report an update of K. variicola and K. Quasipneumoniae genomes correctly classified and a list of isolated genomes obtained from humans, plants, animals and insects, described originally as K. pneumoniae or K. variicola, but known now to be misclassified. Conclusions: This work contributes to recognize the extensive presence of K. variicola and K. quasipneumoniae isolates in diverse sites and samples.The hidden burden of Chikungunya in central Mexico: results of a small-scale serosurvey10.21149/91492021-01-13T00:10:00Z2017-01-20T00:02:00ZCortes-Escamilla, AnaisLópez-Gatell, HugoSánchez-Alemán, Miguel ÁngelHegewisch-Taylor, JenniferHernández-Ávila, MauricioAlpuche-Aranda, Celia Mercedes
<em>Cortes-Escamilla, Anais</em>;
<em>López-Gatell, Hugo</em>;
<em>Sánchez-Alemán, Miguel Ángel</em>;
<em>Hegewisch-Taylor, Jennifer</em>;
<em>Hernández-Ávila, Mauricio</em>;
<em>Alpuche-Aranda, Celia Mercedes</em>;
<br/><br/>
Abstract: Objective: To estimate the seroprevalence of CHKV antibodies and assess correlates of seropositivity at a small geographical scale. Materials and methods: A community-based serosurvey of 387 households in Puente de Ixtla, Morelos (central Mexico). Serum IgG antibodies to CHKV were detected by immunoassay. Results: From 27 April to 29 May 2016, we interviewed and collected blood samples from 387 individuals at the same number of households. A total of 114 (29.5%) participants were seropositive to CHK, 36 (31.6%) of them reported no symptoms of CHKV infection within 12 months before the survey. Conclusion: The estimated seroprevalence to CHKV antibodies was higher than expected by the small number of confirmed cases of CHKV infection reported in Mexico by the National Surveillance System.Prevalencia de anticuerpos frente a parotiditis en niños y adolescentes a dos años de haberse introducido la vacuna SRP10.21149/81382021-01-13T00:10:00Z2017-01-20T00:02:00ZMéndez-Herrera, ArmandoArias-Toledo, EloísaSánchez-Alemán, MiguelOlamendi-Portugal, Ma. LeonidezRuiz-Gómez, JuanDíaz-Ortega, José Luis
<em>Méndez-Herrera, Armando</em>;
<em>Arias-Toledo, Eloísa</em>;
<em>Sánchez-Alemán, Miguel</em>;
<em>Olamendi-Portugal, Ma. Leonidez</em>;
<em>Ruiz-Gómez, Juan</em>;
<em>Díaz-Ortega, José Luis</em>;
<br/><br/>
Resumen: Objetivo: Evaluar la prevalencia de anticuerpos antiparotiditis en niños y adolescentes de México, a dos años de haberse introducido la vacuna SRP. Material y métodos: Se estudiaron 2111 niños (1-9 años) y 2484 adolescentes (10-19 años). Se evaluaron anticuerpos IgG con un kit comercial de ELISA indirecto. Resultados: La seroprevalencia fue 70.6% (IC95% 69.3-71.9) y resultó mayor en adolescentes (83.0%, IC95% 81.5-84.5) que en niños (56.0%, IC95% 53.9-58.11) (OR 3.83; IC95% 3.34-4.39, p=0.0000000). Los niños de 1 a 2 y de 6 a 9 años, que a partir de 1998 formaron parte del grupo blanco de vacunación vs parotiditis, tuvieron mayor seroprevalencia que el grupo de 3 a 5 años no vacunado. Conclusiones: La seropositividad en niños de 1 a 2 y de 6 a 9 años fue probablemente atribuible a vacunación durante 1998-2000 y la de otros grupos etarios a exposición natural relacionada con el tiempo transcurrido en cada cohorte de nacimientos hasta el reclutamiento al estudio.Pathogen-insect interaction candidate molecules for transmission-blocking control strategies of vector borne diseases10.21149/81402021-01-13T00:10:00Z2017-01-20T00:02:00ZZumaya-Estrada, Federico AlonsoRodríguez, María CarmenRodríguez, Mario Henry
<em>Zumaya-Estrada, Federico Alonso</em>;
<em>Rodríguez, María Carmen</em>;
<em>Rodríguez, Mario Henry</em>;
<br/><br/>
Abstract: Objective: To analyze the current knowledge of pathogen-insect interactions amenable for the design of molecular-based control strategies of vector-borne diseases. Materials and methods: We examined malaria, dengue, and Chagas disease pathogens and insect molecules that participate in interactions during their vectors infection. Results: Pathogen molecules that participate in the insect intestine invasion and induced vector immune molecules are presented, and their inclusion in transmission blocking vaccines (TBV) and in genetically modify insect (GMI) vectors or symbiotic bacteria are discussed. Conclusion: Disruption of processes by blocking vector-pathogen interactions provides several candidates for molecular control strategies, but TBV and GMI efficacies are still limited and other secondary effects of GMI (improving transmission of other pathogens, affectation of other organisms) should be discarded.Design and efficacy of an Ecohealth competency-based course on the prevention and control of vector diseases in Latin America10.21149/86072021-01-13T00:10:00Z2017-01-20T00:02:00ZMagaña-Valladares, LauraRodríguez, Mario HenryBetanzos-Reyes, Ángel FranciscoRiojas-Rodríguez, HoracioQuezada-Jiménez, María LauraSuárez-Conejero, Juana ElviraLamadrid-Figueroa, Héctor
<em>Magaña-Valladares, Laura</em>;
<em>Rodríguez, Mario Henry</em>;
<em>Betanzos-Reyes, Ángel Francisco</em>;
<em>Riojas-Rodríguez, Horacio</em>;
<em>Quezada-Jiménez, María Laura</em>;
<em>Suárez-Conejero, Juana Elvira</em>;
<em>Lamadrid-Figueroa, Héctor</em>;
<br/><br/>
Abstract: Objective: To design and analyze the efficacy of an Ecohealth competency-based course on the prevention and control of vector-borne-diseases for specific stakeholders. Materials and methods: Multiple stakeholders and sectors of the region were consulted to identify Ecohealth group-specific competencies using an adjusted analysis matrix. Eight courses based on the competencies were implemented to train EA tutors. The effectiveness of the course was evaluated through the use of paired- t-tests by intervention group. Results: Strategic, tactical, academia and community stakeholder groups and their competencies were identified. An overall gain of 43 percentage points (p<0.001) was observed in terms of competencies score in trained tutors, which further trained 1 033 people. Conclusion: The identification of the stakeholders and their competencies proved to be useful to guide training courses to significantly improve the initial competencies and create a critical mass to further advance the EA in the region.Perfil de resistencia de uropatógenos en pacientes con diabetes en Quito, Ecuador, inquietante panorama10.21149/87562021-01-13T00:10:00Z2017-01-20T00:02:00ZGordillo-Altamirano, FernandoBarrera-Guarderas, Francisco
<em>Gordillo-Altamirano, Fernando</em>;
<em>Barrera-Guarderas, Francisco</em>;
<br/><br/>
Sífilis congénita en el estado de Baja California10.21149/90812021-01-13T00:10:00Z2017-01-20T00:02:00ZConde-González, Carlos Jesús
<em>Conde-González, Carlos Jesús</em>;
<br/><br/>
Respuesta a “Sífilis congénita en el estado de Baja California”10.21149/91052021-01-13T00:10:00Z2017-01-20T00:02:00ZArellano-Estrada, Jorge LuisLópez-Lara, Cinthia SeleneBarreras-Valenzuela, Erendida
<em>Arellano-Estrada, Jorge Luis</em>;
<em>López-Lara, Cinthia Selene</em>;
<em>Barreras-Valenzuela, Erendida</em>;
<br/><br/>
Enfermedad de Chagas: el poder de su confirmación10.21149/88682021-01-13T00:10:00Z2017-01-20T00:02:00ZSánchez García, Dulce CarolinaCastillo-de Haro, Rosa de JesúsNavarro-Guerrero, Juan CarlosVelarde-Félix, Jesús Salvador
<em>Sánchez García, Dulce Carolina</em>;
<em>Castillo-De Haro, Rosa De Jesús</em>;
<em>Navarro-Guerrero, Juan Carlos</em>;
<em>Velarde-Félix, Jesús Salvador</em>;
<br/><br/>
Características familiares y exceso de peso en escolares mexicanos en 201210.21149/86492021-01-13T00:10:00Z2017-01-20T00:02:00ZMartínez Espinosa, Alejandro
<em>Martínez Espinosa, Alejandro</em>;
<br/><br/>
Uso de Internet por adolescentes para temas relacionados con la medicina10.21149/86392021-01-13T00:10:00Z2017-01-20T00:02:00ZReolid-Martínez, Ricardo EnriqueFlores-Copete, MaríaLópez-García, MónicaAlcantud-Lozano, PilarAyuso-Raya, María CandelariaEscobar-Rabadán, Francisco Jesús
<em>Reolid-Martínez, Ricardo Enrique</em>;
<em>Flores-Copete, María</em>;
<em>López-García, Mónica</em>;
<em>Alcantud-Lozano, Pilar</em>;
<em>Ayuso-Raya, María Candelaria</em>;
<em>Escobar-Rabadán, Francisco Jesús</em>;
<br/><br/>
Mieles de abejas sin aguijón en el tratamiento de úlceras de pie diabético10.21149/86042021-01-13T00:10:00Z2017-01-20T00:02:00ZGrajales-Conesa, JulietaIbarias-Toledo, CitlalliRuíz-Toledo, JovaniSánchez, Daniel
<em>Grajales-Conesa, Julieta</em>;
<em>Ibarias-Toledo, Citlalli</em>;
<em>Ruíz-Toledo, Jovani</em>;
<em>Sánchez, Daniel</em>;
<br/><br/>
¿Es el PCA3 costoefectivo en Latinoamérica y el Caribe?10.21149/87182021-01-13T00:10:00Z2017-01-20T00:02:00ZGrández-Urbina, José AntonioPichardo-Rodríguez, RafaelSaldaña-Gallo, Jorge
<em>Grández-Urbina, José Antonio</em>;
<em>Pichardo-Rodríguez, Rafael</em>;
<em>Saldaña-Gallo, Jorge</em>;
<br/><br/>
Análisis microbiológico de muestras de kibbeh crudo revela la presencia de bacterias enteropatógenas10.21149/87032021-01-13T00:10:00Z2017-01-20T00:02:00ZRodriguez-Roque, Santiago ManuelAttie-Habelrih, Maurice GeorgesFigueroa-Espinosa, Roque ArnulfoThomas, Luz EduvigesEscalona-Pacheco, Arnelly JosefinaBáez-Ramírez, Estalina Aimara
<em>Rodriguez-Roque, Santiago Manuel</em>;
<em>Attie-Habelrih, Maurice Georges</em>;
<em>Figueroa-Espinosa, Roque Arnulfo</em>;
<em>Thomas, Luz Eduviges</em>;
<em>Escalona-Pacheco, Arnelly Josefina</em>;
<em>Báez-Ramírez, Estalina Aimara</em>;
<br/><br/>
Evaluación de cuatro métodos para la detección de enterobacterias productoras de BLEE10.21149/87482021-01-13T00:10:00Z2017-01-20T00:02:00ZAcosta-Pérez, GabrielRodríguez-Abrego, GabrielaCastro-Mussot, María Eugenia
<em>Acosta-Pérez, Gabriel</em>;
<em>Rodríguez-Abrego, Gabriela</em>;
<em>Castro-Mussot, María Eugenia</em>;
<br/><br/>
Identificación de parásitos en perros alojados en hogares temporales en Chihuahua, Chihuahua, México10.21149/89372021-01-13T00:10:00Z2017-01-20T00:02:00ZGarcía-Hinojosa, Guillermo AarónÁvila-Huerta, Sandra AlejandraNevárez-Moorillón, Guadalupe VirginiaRodríguez-Zapién, Jesús FranciscoHernández-Castaños, Martín RenatoAdame-Gallegos, Jaime Raúl
<em>García-Hinojosa, Guillermo Aarón</em>;
<em>Ávila-Huerta, Sandra Alejandra</em>;
<em>Nevárez-Moorillón, Guadalupe Virginia</em>;
<em>Rodríguez-Zapién, Jesús Francisco</em>;
<em>Hernández-Castaños, Martín Renato</em>;
<em>Adame-Gallegos, Jaime Raúl</em>;
<br/><br/>
Prueba rápida presuntiva para la detección de falsificaciones de medicamentos biotecnológicos de origen proteico10.21149/85582021-01-13T00:10:00Z2017-01-20T00:02:00ZBadillo-Castañeda, Christian TadeoGarza-Ocañas, Lourdes
<em>Badillo-Castañeda, Christian Tadeo</em>;
<em>Garza-Ocañas, Lourdes</em>;
<br/><br/>
Reconocer los errores diagnósticos, un paso necesario para abordarlos10.21149/84182021-01-13T00:10:00Z2017-01-20T00:02:00ZBarajas-Ochoa, AldoPonce-Horta, Ana María
<em>Barajas-Ochoa, Aldo</em>;
<em>Ponce-Horta, Ana María</em>;
<br/><br/>